Nutraceuticals and Food
General Information
CELNY
Hydroxypropyl Cellulose (HPC) is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.
Our special low viscosity grades offer unique advantages for tablet formulations:
Excellent tablet hardness/friability with fast disintegration and active release times
Ease of use in wet granulation and coating applications
Highest compressibility at low usage level in dry binding applications
Features of CELNY
- Highest efficiency tablet binder
- Soluble in water and polar organic solvents
- Nonionic, nonreactive, nontoxic
- Eight different molecular weight grades produced designed for immediate or sustained release
- Three different particle size grades tailored to wet or dry application
- Minimal lot-to-lot variability enabling Quality By Design
- Global regulatory approval in food and pharma
- 5-year shelf life
- No additives such as silica
Physical and Chemicals Characteristics
Solution Characteristics
Viscosity vs. Solution Concentration (aq.)
Viscosity vs. Solution Concentration (ethanol)
Viscosity vs Temperature Curve
| Gelation Temperature | SSL-20% | SL-10% | L-8% | M-2% | H-1% | VH-1% | Temp.(℃) | 50 | 47 | 45 | 42 | 41 | 41 |
|---|
Thermal Cohesiveness
Moisture content over time
Effect of pH on HPC aqueous viscosity
2% solutions of HPC were measured at various pH at 20°C.
CELNY GRADES & APPLICATIONS
| NISSO HPC | SSL | SL | L | LM | LMM | M | H | VH | |
|---|---|---|---|---|---|---|---|---|---|
| Viscosity (mPa·s) 20℃/2% aq. solution |
2.0-2.9 | 3.0-5.9 | 6.0-10.0 | 11-20 | 21-50 | 150-400 | 1000-4000 | 4001-6000 | |
| Molecular Weight/GPC Method | 40,000 | 100,000 | 140,000 | 180,000 | 280,000 | 700,000 | 1,000,000 | 2,500,000 | |
| AVAILABILITY | Regular Powder (40 mesh pass) D50: 150-190 μm |
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| Fine Powder (100 mesh pass) D50: 80-110 μm |
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| Super Fine Powder (330 mesh pass) D50: 20 μm |
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| APPLICATION |
High Shear Granulation
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Fluidized Bed Granulation
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| Direct Compression Dry Granulation
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| Hot Melt Processing
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| Film Coating
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| Solubility Enhancement
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| Controlled Release Matrix Tablets
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- General Information
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Applications
