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NISSO HPC (Hydroxypropyl Cellulose) is a modified cellulose obtained by reacting propylene oxide with cellulose. The presence of hydroxypropoxy group prevents the hydrogen bonding between the hydroxy groups on the cellulose chain, thereby making HPC soluble.

NISSO HPC was first sold in Japan in 1969 and is globally approved for use in food product and as a pharmaceutical excipient. Nippon Soda has multiple manufacturing lines in Niigata, Japan which have been fully IPEC GMP compliant since 2010.

Main Applications


  • News

    Technical paper, new insights into the use of hydroxypropyl cellulose for drug solubility enhancement, published in Journal of Polymer Science has been uploaded.The paper is available for download.NEW

  • Topics

    13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical TechnologyNEW

    Rotterdam, The Netherland

    March 28-31, 2022

  • Topics


    Pennsylvania Convention Center/Philadelphia, PA

    October 17-20, 2021

  • News

    NEW technical posters presented at PHAMASCI360(AAPS)2020 have been uploaded. The posters are available for download.

  • Topics

    PHARMSCI 360 (AAPS) 2020

    New Orleans, Louisiana

    October 25 - 28, 2020

  • Topics

    2020 Controlled Release Society & Exposition

    Las Vegas, NV

    June 27 – July 1, 2020

  • Topics

    12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology

    Vienna, Austria

    March 23-26 2020

  • Topics

    CPhI worldwide

    Frankfurt, Germany

    November 5-7, 2019

  • Topics

    PHARMSCI 360 (AAPS) 2019

    San Antonio, Texas

    November 3-6, 2019

  • Topics

    CRS Annual Meeting & Exposition

    Valencia, Spain

    July 21-24, 2019